Clinic Observation on 50 Essential Hypertensive Patients Simultaneously Treated with Irbesartan and Nifedipiney

Objective To probe the curative effect of Irbesartan together with Nifedipine on essential hypertension. Methods With random double-bind contrast trail,100 primary hypertensive patients were divided into two groups,the control group treated with Nifedipine +Captopril and the treatment group with Irbesartan + Nifedipine,and changes of their blood pressure and syndromes observed for 1 month. Results The total curative rates of the blood pressure decrease in treatment group (86.0%) and in control group (78.0%) were no difference (P0.05); The total curative rates of the nephropathy healing were significantly different between the treatment group (94.1%) and the control group (56.25%),(P0.05). Conclusions The Irbesartan combined with Nifedipine had no superior effect on the treatment of hypertension than the control group,but had significant effect on the recovery of the kidney function.