Clinical efficacy of low-dose Mifepristone combined with Nvjin Tablet for treating perimenopause dysfunctional uterine bleeding

Objective To analyze the clinical efficacy of low-dose Mifepristone combined with Nvjin Tablet for treating perimenopause dysfunctional uterine bleeding. Methods Sixty-four patients with perimenopause dysfunctional uterine bleeding were selected and randomly divided into the control group and the observation group, each with 32 cases. The patients of the observation group were given low-dose Mifepristone combined with Nvjin Tablet, while the patients of the control group were given low-dose mifepristone only. The levels of estrogen(E2), luteinizing hormone(LH) and progesterone(P) were investigated before and after treatment, as well as endometrial thickness and time of hemostasis. Results The levels of E2, LH and P after treatment were significantly lower than those before treatment(P0.05). The endometrial thickness of the observation group after treatment was(0.7±0.2) cm, which was significantly thinner than that of the control group [(1.1±0.3) cm], P0.05. The time of hemostasis of the observation group after treatment was(32.8±5.9) h, significantly shorter than that of the control group [(44.7±6.6) h], P0.05. Conclusion The low-dose Mifepristone combined with Nvjin Tablet has a significant efficacy for treating perimenopause dysfunctional uterine bleeding, which is deserved promotion.