Relationship between average 24 - hour ambulatory pulse pressure and left ventricular hypertrophy in essential hypertensive patients.

Objective: To investigate the relationship between average 24 hour ambulatory pulse pressure and Left ventricular hypertrophy(LVH) in essential hypertensive patients. Methods: Ambulatory blood pressure monitor (ABPM) was done in 60 hypertensive patients according to clinical stages, which also were divided into two groups-one group with LVH and the other without LVH in left ventricular. Results: (1)The average 24 - hour ambulatory SBP and PP were significantly increased in the group with LVH than those in the group without LVH(P 0.01); (2) A positive correlation was found between average 24 - hour ambulatory PP and LVMI or relative ventricular wall thick(RWT)(.P 0.01) , as well as 24 - hour ambulatory SBP and LVMI or RWT(P 0.01); (3)The level of average 24 - hour ambulatory SBP and PP in the stage Ⅱ and Ⅲ group were marked higher than those in the stage Ⅰ group(P 0.01), and the level of average 24 - hour ambulatory PP in the stage Ⅲ group was higher than that in the stage Ⅱ group(P 0.05). Conclusions: The increase of average 24 - hour ambulatory PP plays the important role in the process of LVH, and could be of prognostic value in estimating the degree of target - organ damage in essential hypertensive patients.