Effects of Pulse,Systolic,Diastolic and Mean Blood Pressure on Left Ventricular Hypertrophy in Patients with Essential Hypertension

Objective To investigate the relationship between pulse pressure (PP),systolic blood pressure(SBP),diastolic blood pressure (DBP),mean blood pressure (MBP) and left ventricular hypertrophy in patients with essential hypertension.Methods Clinical blood pressure,24 h ambulatory blood pressure monitoring and two-dimensional echocardiography were taken in 555 initially untreated patients (275 men and 280 women,aged 47.1±12.7 years).The patients were divided into four groups according to clinical pulse pressure (CPP) or ambulatory pulse pressure (APP) respectively:Group A:PP≤40 mmHg; Group B:40 mmHgPP≤50 mmHg; Group C:50 mmHgPP≤60 mmHg; Group D:PP60 mmHg.They were also divided into age matched 2 groups according to their left ventricular mass index (LVMI),left ventricular hypertrophy (LVH) group (LVMI 134 g/m 2 in man and 110 g/m 2 in woman) were 237 subjects (aged 53.9±10.2 years) and non-LVH group 318 subjects (aged 54.6±9.9 years).Results SBP and PP were significantly higher in LVH group than in non-LVH group.There were no significant difference in DBP between the two groups.Multiple step analysis was showed that SBP was the only independent factor which influenced LVH.Conclusion SBP was one of the most important factors in influencing LVH,neither can DBP nor MAP can induce LVH.