Influencing factors and correction method of platelet detection by hematology analyzer XE5000

Objective To explore the causes and correction method of pseudo-increase and pseudo-decrease in platelet detection by hematology analyzer XE5000.Methods In the cases of abnormal platelet histogram,abnormal graphics of immature cells index(IMI),and specimens of abnormal appearance,the blood samples were taken and rechecked for various reasons.The samples were taken with a 37 ℃ water bath for 15 minutes before counting,the platelet counts were calculated manually,and the types of anticoagulants may be changed.Results Among 27 006 samples,169 cases were found of abnormal platelet histogram,abnormal graphics of IMI,and abnormal specimens appearance.These samples were processed and there were 25 cases of pseudo-increase and 85 cases of pseudo-decrease in platelet counts.Conclusions Through corresponding correcting methods,the platelet count deviation of special samples of hematology analyzer XE5000 can be avoided.