Clinical analysis of 32 cases with sarcoidosis

Objective To explore the clinical features and diagnosis of sarcoidosis.Methods Clinical materials of 32 consecutive patients with biopsy-proven sarcoidosis were retrospectively analyzed.Results The average age was 40.3 years,there were more female patients than male.The main symptoms of respiratory system included cough,chest distress and anhelation.Of extropulmonary presentation,the most common was superficial lymphadenhypertrophy,fever and skin manifestation.X-ray and CT examination results were as follows:bilateral hilar hilifuge was larger than the normal 27 cases,single hilifuge larger than normal 3 cases,mediastinal lymphadenectasis in 28 cases.The sensitivity of serum angiotensin converting enzyme(SACE)was 68.8%.Both the biopsy of lymphonodus of mediastinum through mediastinoscopy and the lung biopsy by video-assisted thoracoscopic surgery were the better methods for the diagnosis of sarcoidosis.Conclusion The clinical presentation of sarcoidosis is varied and nonspecific.Pathological examination should be made for the prevention of missed diagnosis and misdiagnosis.