Clinical Analysis of 30 Patients with Pulmonary Sarcoidosis

Objective To explore the clinical features and diagnosis of sarcoidosis.Methods Clinical materials of 30consecutive patients with biopsy proven sarcoidosis were retrospectively analyzed.Results There were more female patients than males and the ratio of males to females was 1∶2.0.The average age was 42.1 years.There were 1,12,15and 2cases in stage 0,Ⅰ,Ⅱ and Ⅲ respectively.The main symptoms of respiratory tract included cough(46.7%),chest distress(40.0%) and anhelation(36.7%).The main general symptoms included hypodynamia,emaciation and fever.Seventy percent of the patients had high levels of serum angiotensin convertingenzyme.The usual presentation of the chest X-ray and CT was hilar and(or) mediastinal lymphoadenopathy accompanied with diffusive lesion in bilateral lungs or not.The diagnosis was confirmed in 72.7% by the transbronchical mucosa biopsies and 66.7% by the transbronchial lung biopsies.The diagnosis was confirmed in 100% by lymph node biopsy through mediastinoscopy.Conclusion Sarcoidosis is easy to misdiagnosis,and the rate is 43.3%.No specific clinical manifestation may occur in the cases of sarcoidosis.Pathological examination should be made forthe prevention of missed diagnosis and misdiagnosis.