Effect of semen antisperm antibody IgA on main parameters of semen in male infertility patients

Objective To study the effects of the semen antisperm antibody IgA(AsAb) on the main parameters of semen.Methods Sperm samples obtained from 191 patients of male infertility were selected and divided into the semen AsAb positive and negative groups by ELISA method.A comparison among the semen items including the sperm density,sperm activity rate and total activity(PR+NP) were performed between the two groups.Results The sperm density,sperm activity rate and the sperm total activity(PR+NP) in the semen AsAb positive group were lower than those in the semen AsAb negative group with statistical difference between them(P0.01).The percentage of normal morphology sperms in the AsAb positive group had no statistics difference in comparison with the AsAb negative group(P0.05).Conclusion Semen AsAb IgA has no influence on the percentage of normal morphology sperms,but can decrease the sperm density,sperm activity rate and the total activity(PR+NP),which is one of the important factors resulting in the male infertility.