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2012•Journal of Diagnosis and Therapy on Dermato-venereologyRequires access

Expression and Implication of Neutrophil Elastase in Serum of Patients with Psoriasis Vulgaris

Geng Qing-na

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Abstract

Objective:To explore the role of NE in the pathogenesis of psoriasis vulgaris. Methods:Venous blood was collected from 40 individuals with psoriasis vulgaris and 40 control individuals without psoriasis.NE was detected by enzyme-linked immunosorbent assay. Results:Expression level of NE in serum of patients with psoriasis vulgaris was significantly higher than that of normal controls(t=9.07,P0.01),and expression level of NE was positively related to severity of illness(r=0.828,P0.01). Conclusion:Expression level of NE is high in patients with psoriasis vulgaris and it may indicate severity of illness.

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What this paper is about

Objective:To explore the role of NE in the pathogenesis of psoriasis vulgaris. Methods:Venous blood was collected from 40 individuals with psoriasis vulgaris and 40 control individuals without psoriasis.NE was detected by enzyme-linked immunosorbent assay. Results:Expression level of NE in serum of patients with psoriasis vulgaris was significantly higher than that of normal controls(t=9.07,P0.01),and expression level of NE was positively related to severity of illness(r=0.828,P0.01). Conclusion:Expression level of NE is high in patients with psoriasis vulgaris and it may indicate severity of illness.

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Available abstract

Objective:To explore the role of NE in the pathogenesis of psoriasis vulgaris. Methods:Venous blood was collected from 40 individuals with psoriasis vulgaris and 40 control individuals without psoriasis.NE was detected by enzyme-linked immunosorbent assay. Results:Expression level of NE in serum of patients with psoriasis vulgaris was significantly higher than that of normal controls(t=9.07,P0.01),and expression level of NE was positively related to severity of illness(r=0.828,P0.01). Conclusion:Expression level of NE is high in patients with psoriasis vulgaris and it may indicate severity of illness.

Key concepts: Psoriasis, Pathogenesis, Neutrophil elastase, Medicine, Elastase, Immunology, Internal medicine, Gastroenterology

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