2013Journal of Dermatology and VenereologyRequires access

Expression and significance of P-cadherin in psoriasis vulgaris

Zang Fu-lan

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Abstract

Objective To investigate the role of serum P-cadherin in the pathogenesis of psoriasis vulgaris.Methods The serum levels of P-cad in patients with psoriasis vulgaris and controls were measured by enzyme-linked immunosorbent assay(ELISA ).Statistics software of SPSS13.0 and Excel 2003 were applied for data analysis.Results The serum level of P-cad in patients with psoriasis vulgaris was significantly higher than that in control group(P0.01 ),and there was a positive correlation between the serum level of P-cad and the severity of disease.Conclusion P-cadherin may play an important role in the pathogenesis of psoriasis.

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Objective To investigate the role of serum P-cadherin in the pathogenesis of psoriasis vulgaris.Methods The serum levels of P-cad in patients with psoriasis vulgaris and controls were measured by enzyme-linked immunosorbent assay(ELISA ).Statistics software of SPSS13.0 and Excel 2003 were applied for data analysis.Results The serum level of P-cad in patients with psoriasis vulgaris was significantly higher than that in control group(P0.01 ),and there was a positive correlation between the serum level of P-cad and the severity of disease.Conclusion P-cadherin may play an important role in the pathogenesis of psoriasis.

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Available abstract

Objective To investigate the role of serum P-cadherin in the pathogenesis of psoriasis vulgaris.Methods The serum levels of P-cad in patients with psoriasis vulgaris and controls were measured by enzyme-linked immunosorbent assay(ELISA ).Statistics software of SPSS13.0 and Excel 2003 were applied for data analysis.Results The serum level of P-cad in patients with psoriasis vulgaris was significantly higher than that in control group(P0.01 ),and there was a positive correlation between the serum level of P-cad and the severity of disease.Conclusion P-cadherin may play an important role in the pathogenesis of psoriasis.

Key concepts: Psoriasis, Pathogenesis, Cadherin, Medicine, Immunology, Internal medicine, Gastroenterology, Biology

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