Analysis on Detection and Susceptibility of Mycoplasma in Non-gonococcal Urethritis

Objective To determine the mycoplasma infection and the drug susceptibility in non-gonococcal urethritis(NGU) patients.MethodsThe mycoplasma culture was carried out from samples of 450 patients and the susceptibility of mycoplasma to twelve kinds of antimicrobial agents was tested.The mycoplasma positive rate and the drug susceptibility were calculated with a complex mycoplasma kit.Results Of the 450 patients,153 were infected with mycoplasma,and the total positive rate was 34.0%.The positive rates of UU,MH and the mixed infection were 25.6%(115),2.0%(9),and 6.4%(29) respectively.The highest susceptibility rate of UU to twelve antimicrobial agents was Josamycin(99.1%),followed by Doxycycline(96.5%),Minocycline(95.7%),and Tetracyclinum(94.8%).The highest drug resistantce rate of UU was Ciprofloxacin(64.3%),followed by Spaxacin(40.0%),Cravit(40.0%),and Ofloxacin(39.3%).Conclusion It is important to enhance the detection of drug resistance of mycoplasma for guiding appropriate use of drugs and preventing from producing antibiotic-resistant mycoplasma.