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Detection and Drug-susceptibility Analysis of Mycoplasma Isolated from 217 NGU Patients

Xiuli Xu

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Abstract

OBJECTIVE To study the infection and antibiotic drug resistances of mycoplasma from the patients with non-gonococcal urethritis(NGU) in Xi′an areas. METHODS Mycoplasma hominis(Mh) and Ureaplasma urealyticum(Uu) as well as their drug susceptibilities were tested with IST mycoplasma detection kits produced by Bio-Merieux in France. RESULTS The mycoplasma infection rate was 36%,with Uu25.0%, Mh 9.2% and mixed infaction 1.8%, respectively. The drug resistance of Uu was as follows: doxycycline 27.8%, josamycin 9.3%, ofloxacin 14.8%, erythromycin 44.4%. tetracycline 46.3 and pristinamycin 7.4%. The resistances of Mh were 30.0%, 10.0%, 25.0%, 65.0%, 55.0% and 15.0%, respectively. CONCLUSIONS Mycoplasma infection in genitourinary tract is mainly due to Uu infection. Drug resistances of Uu and Mh are different, but they all show high susceptibility to pristinamycine and josamycin, and next ofloxacin and doxycycline.

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OBJECTIVE To study the infection and antibiotic drug resistances of mycoplasma from the patients with non-gonococcal urethritis(NGU) in Xi′an areas. METHODS Mycoplasma hominis(Mh) and Ureaplasma urealyticum(Uu) as well as their drug susceptibilities were tested with IST mycoplasma detection kits produced by Bio-Merieux in France. RESULTS The mycoplasma infection rate was 36%,with Uu25.0%, Mh 9.2% and mixed infaction 1.8%, respectively. The drug resistance of Uu was as follows: doxycycline 27.8%, josamycin 9.3%, ofloxacin 14.8%, erythromycin 44.4%. tetracycline 46.3 and pristinamycin 7.4%. The resistances of Mh were 30.0%, 10.0%, 25.0%, 65.0%, 55.0% and 15.0%, respectively. CONCLUSIONS Mycoplasma infection in genitourinary tract is mainly due to Uu infection. Drug resistances of Uu and Mh are different, but they all show high susceptibility to pristinamycine and josamycin, and next ofloxacin and doxycycline.

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Available abstract

OBJECTIVE To study the infection and antibiotic drug resistances of mycoplasma from the patients with non-gonococcal urethritis(NGU) in Xi′an areas. METHODS Mycoplasma hominis(Mh) and Ureaplasma urealyticum(Uu) as well as their drug susceptibilities were tested with IST mycoplasma detection kits produced by Bio-Merieux in France. RESULTS The mycoplasma infection rate was 36%,with Uu25.0%, Mh 9.2% and mixed infaction 1.8%, respectively. The drug resistance of Uu was as follows: doxycycline 27.8%, josamycin 9.3%, ofloxacin 14.8%, erythromycin 44.4%. tetracycline 46.3 and pristinamycin 7.4%. The resistances of Mh were 30.0%, 10.0%, 25.0%, 65.0%, 55.0% and 15.0%, respectively. CONCLUSIONS Mycoplasma infection in genitourinary tract is mainly due to Uu infection. Drug resistances of Uu and Mh are different, but they all show high susceptibility to pristinamycine and josamycin, and next ofloxacin and doxycycline.

Key concepts: Josamycin, Ureaplasma urealyticum, Mycoplasma hominis, Urethritis, Erythromycin, Mycoplasma, Ofloxacin, Microbiology

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