Evaluation on the efficacy of batroxobin in the treatment of renal insufficiency patients after acute cerebral infarction

Objective:To evaluate the efficacy of batroxobin in the treatment of renal insufficiency patients after acute cerebral infarction.Methods:80 patients were randomly divided into treatment group and control group.Besides the routine treatment in all patients,the patients in treatment group were given the batroxobin,d1 10BU,d3 and d5 both 5 BU in 250mL normal saline,iv drip.Two groups were evaluated the curative effect after 15d,and the changes of anticoagulation, plasminogen and serum lipid in two groups before and after treatment were compared.Results:After one course of treatment,there was significant difference in the curative rate (73.8% vs 34.2%, P 0.01) between treatment group and control group.Conclusion:Batroxobin is effective in the treatment of renal insufficiency patients after acute cerebral infarction.