2004•Chinese Journal of Infection ControlRequires access
Distribution and antimicrobial resistance of Acinetobacter baumannii infection
Wu Jin
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Abstract
Objective To study the distribution and antimicrobial resistance of Acinetobacter baumannii infection in a hospital. Methods Two hundred and fifty four strains of Acinetobacter baumannii isolated from patients with infection from July 2000 to July 2003 were collected and antimicrobial susceptibility tests were performed. Results One hundred and eighteen strains ( 46.46% ) of Acinetobacter baumannii were from intensive care unit, forty strains ( 15.75% ) were from respiratory unit. The resistant rates of the strains to the third generation cephalosporin and ciprofloxacin were both more than 50.00%; the resistant rate to imipenem was the lowest ( 16.93% ), followed by meropenem (22.05%) and ampicillin/sulbactam ( 22.20% ); 185 strains ( 72.83% ) were multiply resistant to antimicrobial agents. The antimicrobial resistance of strains isolated from different wards had significant difference (P 0.05 ). Conclusion Carbapenem and ampicillin/sulbactam still had a strong antimicrobial activity against Acinetobacter baumannii. Antimicrobial agents should be used rationally to decrease multiply resistance.