The Survey of Normal Pregnant Women's Routine Blood Coagulation Reference Interval in Different Periods and Post Partum

Objective: To establish our lab’s reference interval of routine blood coagulation in different periods and post partum by analysing their blood coagulation indices.Method: The prothrombin time(PT),activated partial thrombopastin time(APTT),fibrinogen(FIB) and thrombin time(TT) were detected by using the hemagglutinin analyzer.Result: The results of early pregnancy and 72 hours after delivery have no significant difference(P0.05) compared with the healthy control group.The levels of PT and APTT in middle and late pregnant were lower than the health control group and showed statistically significant(P0.050.01).The FIB was obviously higher and showed significant difference(P0.01) compared with the healthy control group.There was no significant difference in TT level between the two groups.Conclusion: The blood of pregnant women is in a hypercoagulable state before delivery and it returns to normal at 72 hours after delivery.Dynamic detection of four indices of blood coagulation in connection with our lab’s condition,anglyzer,reagent,establishing our lab’s reference interval of routine blood coagulation in normal perinatal women has important clinical significance in monitoring and prevention of postpartum hemorrhage in lying-in women and in evaluation of their prognosis.