2009•Journal of clinical and experimental medicineRequires access
The change in blood coagulation before and after natural delivery and its clinical significance
Wei Liang Gan
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Abstract
Objective To study changes in coagulation function in pregnant women before and after their natural delivery.Methods Tomeasure PT,APTT,TT and FIB in 146 cases of pregnant women before and after their natural delivery and 30 healthy non-gestational women were selected for control.Results There were four indices of blood coagulation in pregnant women before delivery showed significantly different(P 0.01)in comparison with controls.There was no significant difference between post-delivery group and control group(P 0.05).Conclusion The blood of pregnant women is in a hypercoagulable state before natural delivery and it returns to normal at 72 hours after delivery.Dynamic detection of four indices of blood coagulation may perfectly and completely reflect the blood coagulation function of pregnant women and lying-in women,and it has important clinical significance in monitoring and prevention of postpartum hemorrhage in lying-in women and in evaluation of their prognosis.