Pseudomonas Aeruginosa Infection and Its Drug Resistance in Our Hospital in 2008

OBJECTIVE:To analyze the risk factors and drug resistance of pseudomonas aeruginosa infection in our hospital to promote rational use of antibacterials. METHODS:The risk factors and antibiotic resistance of 129 patients with pseudomonas aeruginosa infection in our hospital in 2008 were reviewed retrospectively. RESULTS:The risk factors of pseudomonas aeruginosa infection included chronic diseases,invasive procedures,previous treatment with antimicrobial drugs and hormones,ICU admission, hospital stay longer than 60 days etc. The drugs to which pseudomonas aeruginosa showing resistance in ascending order were ami-kacin(21.3%),imipenem(30.2%),and ceftazidime(70.6%),piperacillin(70.4%),cefepime(62.3%),piperacillin/tazobactam(62.1%),and cefoperazone /sulbactam(61.0%). CONCLUSION:Multi-drug resistance was serious for pseudomonas aeruginosa in our hospital,which resulted in difficulties in the choice of antibiotics. It is imperative to strengthen rational use of antimicrobial drugs in our hospital.