Extraction process of shenling granules

Aim To optimize the extracting technique conditions of shenling granules.Methods With the obtaining rate of extract and the total content of the magnolol and honokiol presented in the extract as the indexes for the ethanol extraction process,and with the obtaining rate of extract and the content of total glycyrrhizinic acid monoammonium salt presented in the extract as the indexes for the water extraction process,orthogonal design was used to optimize the conditions for the extraction process respectively.Results The optimal conditions for the ethanol extraction of shenling granules was as follows:10 times of 70% ethanol was added,reflux 3 times,1.5 hours each time.The optimal process of the water extraction for shenling granules was to add water 12 times,decocting 2 times,2 hours each time.Conclusion The extracting method is reasonable,stable,and suitable to industrialized production.