Efficacy Observation of Yinzhihuang Oral Liquid in the Treatment of Neonatal Pathologic Jaundice

OBJECTIVE: To observe the efficacy and safety of Yinzhihuang oral liquid in the treatment of neonatal pathologic jaundice. METHODS: From Oct. 2008 to Sep. 2009 in our hospital, 360 newborns with pathologic jaundice were randomly divided into treatment group Ⅰ, treatment group Ⅱ and control group with each group of 120 cases. Treatment group Ⅰ was given Yinzhihuang oral liquid, treatment group Ⅱ was given Tuihuang mixture and control group was untreated. After 5 days, the decreases of neonatal jaundice in 3 groups were observed. RESULTS: The treatment effect of treatment group Ⅰ was similar to treatment group Ⅱ(P0.05), the total effective rate and the decrease of neonatal in treatment groupⅠ was better than that of control group, there was significant difference (P0.05). There were little and slight adverse drug reactions. CONCLUSION: Yinzhihuang oral liquid is safe and effective drug for neonatal pathologic jaundice. The therapeutic efficacy of it is similar to Tuihuang mixture with little adverse drug reactions. Yinzhihuang oral liquid is a solution to inconvenience brought by inadequate condition for admixture of Tuihuang mixture in sorne hospitals.