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2001•Journal of Qilu OncologyRequires access

A Clinical Study on High Intensity Focused Ultrasound in Treating Patients with Advanced Pancreatic Carcinoma

Xie De

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Abstract

Objective To observe the therapeutic and side effects of hight intensity focused ultrasound(HIFU)in treating patients with advanced pancretic carcinoma.Methods Thirteen patients with advanced pancreatic carcinoma received 91(average 7)times of HIFU therapy,4 cases of them combimed low dose 5 FU chemotherapy.Results 2 cases acquired CR and 4 PR,The response rate was 46 2%.The clinical benefit response(CBR)was 92 3% and the median survival was 7 0 months.There were few toxicities except one case having obstruct jaundice after 5 months later of HIFU therapy.Conclusions The preliminary results show that HIFU has a high efficacy and quite safety for advanced pancreatic carcinoma,it is worthy of futher clinical trail.

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What this paper is about

Objective To observe the therapeutic and side effects of hight intensity focused ultrasound(HIFU)in treating patients with advanced pancretic carcinoma.Methods Thirteen patients with advanced pancreatic carcinoma received 91(average 7)times of HIFU therapy,4 cases of them combimed low dose 5 FU chemotherapy.Results 2 cases acquired CR and 4 PR,The response rate was 46 2%.The clinical benefit response(CBR)was 92 3% and the median survival was 7 0 months.There were few toxicities except one case having obstruct jaundice after 5 months later of HIFU therapy.Conclusions The preliminary results show that HIFU has a high efficacy and quite safety for advanced pancreatic carcinoma,it is worthy of futher clinical trail.

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Available abstract

Objective To observe the therapeutic and side effects of hight intensity focused ultrasound(HIFU)in treating patients with advanced pancretic carcinoma.Methods Thirteen patients with advanced pancreatic carcinoma received 91(average 7)times of HIFU therapy,4 cases of them combimed low dose 5 FU chemotherapy.Results 2 cases acquired CR and 4 PR,The response rate was 46 2%.The clinical benefit response(CBR)was 92 3% and the median survival was 7 0 months.There were few toxicities except one case having obstruct jaundice after 5 months later of HIFU therapy.Conclusions The preliminary results show that HIFU has a high efficacy and quite safety for advanced pancreatic carcinoma,it is worthy of futher clinical trail.

Key concepts: High-intensity focused ultrasound, Medicine, Pancreatic carcinoma, Carcinoma, Radiology, Chemotherapy, Jaundice, Ultrasound

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