Methylprednisolone Sequential Therapy in Idiopathic Thrombocytopenic Purpura

Objective The aim was to evaluate the clinical efficacy of methylprednisolone sequential therapy in idiopathic thrombocytopenic purpura (ITP).Methods 22 cases of ITP in the treatment group were given methyl- prednisolone sequential therapy,whereas 19 cases of ITP in the control group were given dexamethasone/prednisone, then the clinical efficacy and security were compared between two groups.Result The total efficiency in the treatment group was 87% and it was 72% in the contral group.There was no significant difference between two groups(P＞0.05).The time during which the platelet was the lowest in the treatment group was shorter than that in the control group,and the platelet increased time was shorter too (P＜0.05).The times of being introduced platelet in the treatment group was less than that in the control group(P＜0.05).Pre-and post-therapy,the decreased level of serum PAIgG in the treatment group was larger than that in the control group (P＜0.05).Conelusion The effective of methylprednisolone sequential therapy ITP was fast and sustained while the side effect was limited.