Treatment of 30 Cases of Idiopathic Thrombocytopenic Purpura with Modified Xiaochahu Granule

OBJECTIVE To investigate into the therapeutic effect and side effect of modified Xiaochahu Granule used in combination with prednisone in the treatment of idiopathic thrombocytopenic purpura(ITP) and to compare the effect with simple prednisone.METHOD 60 ITP patients were randomly divided into a treatment group of 30 patients(modified Xiaochahu Granule plus prednisone) and a control group of 30 patients(simple prednisone).RESULT The effective rates obtained in the treatment group and control group were 86.76% and 60% respectively.In the treatment group,the average time for the drug to take effect was(7±3) days and the time for the hormone to reduce in amount was(15±4) days;in the control group,these figures were(14±4) and(23±6) respectively.The cases with over 50×10~9/L of blood platelet after six months accounted for 56.67% in the treatment group and 26.67% in the control group.Side effect occurrence rates in the treatment and control groups were 53.33% and 100% respectively.Marked differences were found between the two groups(P0.05).CONCLUSION The combined used of modified Xiaochahu Granule and prednisone in the treatment of idiopathic thrombocytopenic purpura is effective with the effect of prolonging validity duration and reducing the side effect of the hormone.