2014•Liaoning zhongyi zazhiRequires access
Effect of Xuanfu Daizhe Decoction on FT4 and TSH of Serum in Reflux Ephagitis Rat Model
Cui Ha
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Abstract
Objective: To observe the effect of Xuanfu Daizhe Decoction on reflux ephagitis and to discuss the action mechanism. Methods: The rat model was made with esophageal duodenal end side anastomosis. They were randomly divided into five groups and treated with different methods. And then the pathological change of esophageal mucosa and FT4 and TSH of serum were observed. Results: ①The body mass increased values in traditional Chinese medicine( TCM) and Western medicine( WM) were significantly different with model section. ②The naked eye observing scores in TCM group and WM group were significantly different from that of the model group. ③The FT4 and TSH of serum in TCM and WM groups were significantly different compared with those of the model group. Conclusion: Xuanfu Daizhe Decoction can improve the relaxation of esophageal sphincter of the model rats and the action mechanism may be the concentrations of FT4 and TSH were improved and the esophageal muscle contract amplitude and contract rate were promoted and strengthening the function of the digestive movement.