Postoperative analgesia with flurbiprofen axetil combined with sufentanil in patients underwent cardiac surgery

Objective To access the analgesia effect and side effect of flurbiprofen axetil combined with sufentanil.Methods Thirty-eight patients underwent cardiac surgery were randomly divided into two groups with nineteen cases each.Group S was given sufentanil 250 μg diluted to 125 ml via PCIA after surgery.Group F was given sufentanil 125 μg plus flurbiprofen axetil 150 mg diluted to 125 ml via PCIA after surgery.The PCIA pump was set at a rate of 0.2 ml/h,bolus dose was 0.8 ml,lockout time interval was 10 min.Analgesia grade was accessed,vital sign and side effects were recorded.Results There was no significant difference in analgesia grade between two groups.The side effects were lower in group F than those in group S.Conclusion Flurbiprofen axetil combined with sufentanil can obtain similar analgesia effects to sufentanil alone,but can reduce side effects and fever temperature.