2008•Journal of Shenyang Medical CollegeRequires access

The clinical observation of doxofylline injection for 70 case of bronchial asthma and COPD

Yang Hong-yu

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Abstract

objective:To observe the effect of doxofylline injection for patients with bronchial asthma and COPD.Methods:Comparison between doxofylline and anfylline.70 case of the remedial group were treated for a week with intravenous infusion of 300mg of doxofylline injection which was added to 250ml of glucose,once a day.The control group were treated for a week with intravenous infusion of 250mg of aminophylline injection which was added to 250ml of glucose,once a day.The clinical curative effect of two group of patients was compared in the post-treatment.The lung function parameters of two groups are compared after post-treatment.Result:In the curative effect,the total effective rate was 85.6% in the doxifylline group and that was 71.7% in control group.In FEV1(forced expiratory volume one second),the total effective rate was 88.5% in the remedial group and that was 75.0% in control group.In the ratio of FEV1 to FVC(force vital capacity),the total effective rate was 87.1% in the remedial group and that was 73.3% in control group.The incident rate of adverse effect was lower than that of the control group obviously.There were significant differences between the doxofylline group and the control group(P0.05).Conclusion:The effect of doxofylline injection for patients with bronchial asthma and COPD is obvious.

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objective:To observe the effect of doxofylline injection for patients with bronchial asthma and COPD.Methods:Comparison between doxofylline and anfylline.70 case of the remedial group were treated for a week with intravenous infusion of 300mg of doxofylline injection which was added to 250ml of glucose,once a day.The control group were treated for a week with intravenous infusion of 250mg of aminophylline injection which was added to 250ml of glucose,once a day.The clinical curative effect of two group of patients was compared in the post-treatment.The lung function parameters of two groups are compared after post-treatment.Result:In the curative effect,the total effective rate was 85.6% in the doxifylline group and that was 71.7% in control group.In FEV1(forced expiratory volume one second),the total effective rate was 88.5% in the remedial group and that was 75.0% in control group.In the ratio of FEV1 to FVC(force vital capacity),the total effective rate was 87.1% in the remedial group and that was 73.3% in control group.The incident rate of adverse effect was lower than that of the control group obviously.There were significant differences between the doxofylline group and the control group(P0.05).Conclusion:The effect of doxofylline injection for patients with bronchial asthma and COPD is obvious.

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Available abstract

objective:To observe the effect of doxofylline injection for patients with bronchial asthma and COPD.Methods:Comparison between doxofylline and anfylline.70 case of the remedial group were treated for a week with intravenous infusion of 300mg of doxofylline injection which was added to 250ml of glucose,once a day.The control group were treated for a week with intravenous infusion of 250mg of aminophylline injection which was added to 250ml of glucose,once a day.The clinical curative effect of two group of patients was compared in the post-treatment.The lung function parameters of two groups are compared after post-treatment.Result:In the curative effect,the total effective rate was 85.6% in the doxifylline group and that was 71.7% in control group.In FEV1(forced expiratory volume one second),the total effective rate was 88.5% in the remedial group and that was 75.0% in control group.In the ratio of FEV1 to FVC(force vital capacity),the total effective rate was 87.1% in the remedial group and that was 73.3% in control group.The incident rate of adverse effect was lower than that of the control group obviously.There were significant differences between the doxofylline group and the control group(P0.05).Conclusion:The effect of doxofylline injection for patients with bronchial asthma and COPD is obvious.

Key concepts: Medicine, Aminophylline, COPD, Anesthesia, Asthma, Adverse effect, Vital capacity, Lung function

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