2004•Chinese New Drugs JournalRequires access
Comparison of the efficacy of cefdinir and cefteram in treatment of acute bacterial urinary tract infections
Yong Liu
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Abstract
Objective:To compare the efficacy and safety of cefdinir and cefteram in treatment of acute bacterial urinary tract infections. Methods: 26 patients with mild to moderate acute pyelonephritis or acute cystitis were randomly and equally divided to receive cefdinir or cefteram, in a dose of 100mg 3 times daily for 7d in both groups. Results:The bacterial eradication rate was 100.0% for both groups,the cure rate was 76.9% for both groups,and the total effective rate was 100.0% for cefdinir group and 92.3% for cefteram group. The incidence of ADRs was 7.7% for both groups. No significant difference was observed in all the parameters between groups. Conclusion: Cefdinir is safe and effective in treatment of mild to moderate acute bacterial urinary infections caused by bacteria sensitive to cefdinir.