Observation of Therapeutic Effects of the Conventional Therapy plus Melitracen and Flupentixol in the Treatment of Functional Dyspepsia

OBJECTIVE: To observe the therapeutic effects of the conventional therapy plus Melitracen and Flupentixol in the treatment of functional dyspepsia(FD).METHODS: 320 FD cases were divided into gastrointestinal dyskinesis type(Type A,n=120 cases),ulceration type(Type B,n=100 cases),and nonspecific type(Type C,n=100 cases) based on their clinical symptoms.Patients of different clinical types were randomly assigned to receive conventional therapy alone or in combination with Melitracen and Flupentixol for 4 weeks.The curative effects were observed using gastrointestinal symptom rating scale(GSRS) and the total effective rate were computed.RESULTS: After treatment,the GSRS score of 3 different clinical types of FD in the combination therapy group versus the conventional therapy alone were 1.53±1.68 vs.3.10±1.78,2.02±1.63 vs.3.48±1.80 and 3.46±2.95 vs.5.18±3.21 respectively(P0.01),the total effective rates were 91.4% vs.69.4%,86.0% vs.68.0% and 90.2% vs.77.6% respectively(P0.01).CONCLUSION: Conventional therapy plus Melitracen and Flupentixol can improve the symptoms and the total effective rate of FD.