2010•Journal of Apoplexy and Nervous DiseasesRequires access

The study on the interleukin-6 gene-174C/G polymorphism of cerebral infarction inTangshan Hans population

Jiang Zhang, Dali Wang, Naiyao Chen

Abstract

Objective To investigate the relationship between interleukin-6 gene-174C/G polymorphism and cerebral infarction in Tangshan Hans population.Methods 118 patients with cerebral infarction and 154 normal people were recruited.All participants were genotyped for the interleukin-6 gene at the-174C/G locus using PCR-based restriction fragment length polymorphism method.Results Genotype of interleukin-6 gene-174 was all GG.Conclussion There was not interleukin-6 gene-174G/C polymorphism in Tangshan Hans population.Interleukin-6 gene-174C/G polymorphism may be not associated with susceptibility to cerebral infarction

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Key concepts: Genotype, Locus (genetics), Gene polymorphism, Cerebral infarction, Polymorphism (computer science), Population, Gene, Interleukin