2009•China Surfactant Detergent & CosmeticsRequires access
Determination of preservatives in cosmetics by reversed-phase high performance liquid chromatography
Yang Feng
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Abstract
A reversed-phase high performance liquid chromatography was developed for determination of preservatives in cosmetics,including diazo alkyl urea,methyl-p-hydroxy benzoate and propyl-p-hydroxy benzoate.A Waters XTerra Ms C18(5 μm,4.6 mm i.d×250 mm)column was used with a mobile phase consist of acetonitrile-water and gradient elution.The wavelength 254 nm was selected for detection.The recovery lies 97.30%～102.00% and the relative standard deviation lies 3.6%～8.2%.