Synthesis of p-Tolylbenzyl Ether by Phase Transfer Catalysis under Microwave Irradiation
Peng Shao-hui
Abstract
Peng Shao-hui
Abstract
The p-tolyl benzyl ether was synthesized by reaction of p-cresol and benzyl chloride in H2O-95% ethanol as solvent by phase transfer catalysis under microwave irradiation.The proper technological conditions were identified as follows: n(p-cresol) : n(benzyl chloride) : n(sodium hydroxide)= 1:1.1:1.1,microwave power 400 W and microwave irradiation time 6 min.The average yield of p-tolyl benzyl ether achieves 96.21%.
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The p-tolyl benzyl ether was synthesized by reaction of p-cresol and benzyl chloride in H2O-95% ethanol as solvent by phase transfer catalysis under microwave irradiation.The proper technological conditions were identified as follows: n(p-cresol) : n(benzyl chloride) : n(sodium hydroxide)= 1:1.1:1.1,microwave power 400 W and microwave irradiation time 6 min.The average yield of p-tolyl benzyl ether achieves 96.21%.
Key concepts: Catalysis, Ether, Sodium hydroxide, Chemistry, Microwave irradiation, Solvent, Ethanol, Benzyl chloride