2006•Huaxi yaoxue zazhiRequires access
Determination of berberine hydrochloride,palmatine hydrochloride and jatrorrhizine hydrochloride in Cortex Phellodendri Chinensis by HPLC
Meng Ye
Open publisher page 2 citations
Abstract
OBJECTIVE To establish a method for quality estimation of Cortex Phellodendri Chinensis.METHODS HPLC method was adopted to determine the content of berberine hydrochloride,palmatine hydrochloride and jatrorrhizine hydrochloride,respectively.RESULTS AND CONCLUSION The average content of berberine hydrochloride of Cortex Phellodendri Chinensis in 9 producing districts of Sichuan was 50.5840 mg·g~(-1),which is 7.38 times of that of Cortex Phellodendri Amurensis(6.8583 mg·g~(-1)).Inclusively,the content of berberine (hydrochloride) in Cortex Phellodendri Chinensis of Yingjing in Sichuan was of the most level,which reaches 86.5381 mg·g~(-1).It suggests that Yingjing to be a trueborn place for producing Cortex Phellodendri Chinensis.The average content corcerning palmatine hydrochloride of Cortex Phellodendri Chinensis in 9 producing districts is 0.1296 mg·g~(-1),while that of Cortex Phellodendri Amurensis is 3.1310 mg·g~(-1),which is(24.16) times of the former.The average content concerning jatrorrhizine hydrochloride of Cortex Phellodendri Chinensis is 0.2956 mg·g~(-1),and that of Cortex Phellodendri Amurensis is 0.2883 mg·g~(-1),both of which have subtle difference.