2005•Zhōnghuá yàoxué zázhìRequires access

Sutdy on preparation and in vitro release of oxymatrine sustained-release tablets

Miao Cai-yun

Abstract

OBJECTIVE To prepare oxymatrine sustained-release tablets and evaluate the drag release property.METHODS Oxyma-trine sustained-release tablets were prepared with HPMC by wetting granulating method. The release rates of the sustained-release tablets were determined and the effects of the release medium were investigated. RESULTS The prepared sustained-release tablets had an obvious sustained-release effect, and the drug release pattern folloloed the first order kinetics[ln(100- Q) =- 0.11t+4.50,r = 0.9998].CONCLUSION The sustained-release tablets reach the expectable results with its reasonable formulation and simple technology.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Oxymatrine, Chromatography, Chemistry, Wetting, Controlled release, Pharmacology, Materials science, Medicine