Clinical Study on Application of Yiqi Huoxue Huatan Formula for Treatment on Cerebral Ischaemic Stroke

Objective:By observing Yiqi Huoxue Huatan Formula's clinical application for treatment on the Cerebral Isehaemic Stroke(CIS),we verified the effect of Yiqi Huoxue Huatan Formula in clinical and explored its mechanism of treatment on CIS,furthermore,the evidence for clinical popularization of the therapy can be provided.Methods:According to diagnosis standards in the study,59 patients were randomly classified into two groups:the comparison group with 28 cases were given medicine to treat regularly,the therapy group with 31 cases were given Yiqi Huoxue Huatan Formula besides the medicine as the same as the comparison group.The period of treatment contains two weeks.The nerve functions deficiency and the clinic grade of stroke were evaluated,then the level of neuron-specific enolase(NSE) and endothelin(ET) were compared respectively before treatment and post-treatment between two groups.Results:On the clinical effect,the total effective rate of the therapy group treated with the Yiqi Huoxue Huatan Formula was 90.32%,which exceeded obviously that of the comparison group(78.57%).On the Chinese traditional medicine symptom of CIS,the total effective rate of the Yiqi Huoxue Huatan Formula was 90.33%,which was highly prior to that of the comparison group(82.14%),and the difference index was in statistics(P0.05).The difference was remarkable in the scores of nerve function deficiency(P0.05).Simultaneously,there was remarkable decrease of the levels of NSE and ET in the therapy group in contrast with that of the comparison group(P0.05).Conclusion:YiqiHuoxue Huatan Formula's clinical effect in the treatment of the Cerebral Isehemic Stroke(CIS) is remarkable as well as safe,the possible protective mechanism on cerebral cells is by means of inhibiting NSE and ET releasing.