Clinical Significance of Serum Total Bile Acid in the Diagnosis of Neonatal Jaundice

Objective To discuss the clinical application value of total bile acid in the diagnosis and treatment of neonatal jaundice through the detection of total bile acid(TBA)level.Methods Enzymatic cycling method was used to test serum total bile acids in physiologic jaundice and pathological jaundice and detect the index of liver function.The results were compared.Results The DBIL,ALT,TBA of physiological jaundice group were lower than pathological jaundice group(P0.05),especially the DBIL and TBA value(P0.01).The abnormal ALT rate and abnormal TBA rate of physiological jaundice group were significantly lower than the pathological jaundice group(P0.01).Conclusion Serum TBA test can be used to diagnose pathological jaundice babies well,which can reflect the important index of different degrees of cholestasis and substantive liver damage,thus can provide reference for clinical diagnosis and treatment.