Clinical comparitive research of treatment with levofloxacin for the patients with respiratory system Infection

OBJECTIVE To evaluation the efficacy and safety of levofloxacin hydrochloride in treatment of bacterial respiratory system infection disease. METHOD A clinical randomized controlled trial was conducted. 60 patients with bacterial respiratory system infection were randomly allocated to therapeutic group and control group. 30 cases in the therapeutic group were treated with levofoxacin hydrochloride, the other 30 patients in the control group were treated with levofloxacin lactace.RESULTS Clinical effective rates were 73.3%in therapic group and 66.7% in control group. Whereas the bacterial clearance rates were 76.7% and 59.3% respectively; the adverse drug effect rates were 3.3% and 6.7% respectively. There was no significant different between the two groups.CONCLUSION The levofloxacin hydrachloride was effective and safe in the treatment of bacterial respiratory system infection and was bioequivalence with levofloxacin lactace.