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2000•Chinese New Drugs JournalRequires access

Clinical trial of levofloxacin HCl in treatment of bacterial infections

Xu Zhi

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Abstract

Objectives:To evaluate the efficacy and safety of levofloxacin HCl in comparison with levofloxacin lactate in treatment bacterial infections.Methods:162 patients were included in the multicenter,randomized,controlled study.They included 121 cases of randomized,controlled study and 41 cases of open trial.The dose was 0.1g,bid for 7～14d.Results:In treatment of respiratory and urinary infections,no statistical significant difference in effective rate,bacterial eradication rate and MIC were observed between the active and control drug.Conclusions:In treatment of respiratory and urinary infections,levofloxacin HCl is as effective as levofloxacin lactate. [

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What this paper is about

Objectives:To evaluate the efficacy and safety of levofloxacin HCl in comparison with levofloxacin lactate in treatment bacterial infections.Methods:162 patients were included in the multicenter,randomized,controlled study.They included 121 cases of randomized,controlled study and 41 cases of open trial.The dose was 0.1g,bid for 7～14d.Results:In treatment of respiratory and urinary infections,no statistical significant difference in effective rate,bacterial eradication rate and MIC were observed between the active and control drug.Conclusions:In treatment of respiratory and urinary infections,levofloxacin HCl is as effective as levofloxacin lactate. [

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Available abstract

Objectives:To evaluate the efficacy and safety of levofloxacin HCl in comparison with levofloxacin lactate in treatment bacterial infections.Methods:162 patients were included in the multicenter,randomized,controlled study.They included 121 cases of randomized,controlled study and 41 cases of open trial.The dose was 0.1g,bid for 7～14d.Results:In treatment of respiratory and urinary infections,no statistical significant difference in effective rate,bacterial eradication rate and MIC were observed between the active and control drug.Conclusions:In treatment of respiratory and urinary infections,levofloxacin HCl is as effective as levofloxacin lactate. [

Key concepts: Levofloxacin, Medicine, Randomized controlled trial, Urinary system, Internal medicine, Clinical trial, Antibiotics, Microbiology

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