ScholarLens Back to search
2004•Journal of Lanzhou Medical CollegeRequires access

The clinical significance of TNF-α and IL-8 in serum of patients with cerebral infarction

Zhang Yon

Open publisher page 0 citations

Abstract

Objective To investigate the significance of serum levels(TNF-α、IL-8) in patients with cerebral infarction(CI). Methods The serum levels of TNF-α and IL-8 were measured in 62 patients with (CI)and 48 healthy subjects by ELISA. The volume of CI were determined in 62 patients with CI.Results The serum levels of TNF-α and IL-8 in patients with CI were significantly higher compared to those in control group. The positive correlation between the serum levels(TNF-α、IL-8) and the volume of CI had been shown.Conclusion The serum level of TNF-αand IL-8 were significantly elevated in the patients with CI,which suggested that TNF-α and IL-8 may play an important role in the pathogenesis of CI.

About this research paper

What this paper is about

Objective To investigate the significance of serum levels(TNF-α、IL-8) in patients with cerebral infarction(CI). Methods The serum levels of TNF-α and IL-8 were measured in 62 patients with (CI)and 48 healthy subjects by ELISA. The volume of CI were determined in 62 patients with CI.Results The serum levels of TNF-α and IL-8 in patients with CI were significantly higher compared to those in control group. The positive correlation between the serum levels(TNF-α、IL-8) and the volume of CI had been shown.Conclusion The serum level of TNF-αand IL-8 were significantly elevated in the patients with CI,which suggested that TNF-α and IL-8 may play an important role in the pathogenesis of CI.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the significance of serum levels(TNF-α、IL-8) in patients with cerebral infarction(CI). Methods The serum levels of TNF-α and IL-8 were measured in 62 patients with (CI)and 48 healthy subjects by ELISA. The volume of CI were determined in 62 patients with CI.Results The serum levels of TNF-α and IL-8 in patients with CI were significantly higher compared to those in control group. The positive correlation between the serum levels(TNF-α、IL-8) and the volume of CI had been shown.Conclusion The serum level of TNF-αand IL-8 were significantly elevated in the patients with CI,which suggested that TNF-α and IL-8 may play an important role in the pathogenesis of CI.

Key concepts: Medicine, Pathogenesis, Tumor necrosis factor alpha, Clinical significance, Internal medicine, Positive correlation, Cerebral infarction, Gastroenterology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The clinical significance of TNF-α and IL-8 in serum of patients with cerebral infarction — Research Paper | ScholarLens