α-glucosidase inhibitory activity of Osmanthus fragrans Lour. (Wanyingui,Yaotiaoshunv and Guifeihong)

Objective: To investigate α-glucosidase inhibitory activity of three species Guifeihong,Wanyingui and Yaotiaoshunv Osmanthus fragrans Lour.petroleum ether extracts.Methods: The different extracts were extracted by Soxhlet,and α-glucosidase inhibitory activity was screened by the 96-microplate-based method.Results: The leaves and flowers of three species O.fragrans showed good inhibitory activity.The petroleum ether extract of Guifeihong had the highest inhibitor activity(IC50=68.26 mg/L),and followed by Wanyingui(IC50=145.25 mg/L) and Yaotiaoshunv(IC50=145.08 mg/L),which is more lower than that of Acarbose(IC50=1081.27 mg/L).Conclusion: All extracts from Osmanthus fragrans Lour.have good inhibitory activity of α-glucosidase.