Effect of Danhong injection on neurological function and serum hs-CRP, TNF-á and IL-6 levels in patients with acute cerebral infarction

Objective To investigate the effects of Danhong injection on the neurological function and serum highsensitivity C reactive protein(hs-CRP), TNF-a and IL-6 levels in patients with acute cerebral infarction(ACI). MethodsEighty ACI cases were randomly divided into observation and control groups. In addition to the conventional treatment, Danhong injection and low molecular citicoline were supplemented in observation and control groups, respectively. The neurological function and serum hs-CRP, TNF-a and IL-6 levels were compared between two groups. Results Compared with the daily living activity(Barthel index) increased, while NIH Stroke Scale and serum hs-CRP, TNF-a and IL-6 levels decreased after treatment in both groups, especially in observation group(P0.01). Conclusion Danhong injection can inhibit expression of inflammatory cytokines, and play a protective role in the cerebral injury.