Effect of Dan Hong injection on acute cerebral infarction in patients with serum cytokine levels

Objective To study the Danhong injection on acute cerebral infarction in patients with neurological deficit scores and cytokines TNF-α,IL-1 and IL-6 effects. Methods A randomi-zed controlled by the principles of the 60 cases of onset of acute cerebral infarction within 72 h were divided into control group and treatment group,30 cases in each group. Control group was given conventional therapy,the treatment group on the basis of conventional therapy for 40 mL Danhong injection into the 250 mL 0.9% sodium chloride injection in the intravenous drip,once daily treatment groups were 14 d. CSS score measured before and after treatment,serum TNF-α,IL-1 and IL-6 levels. Results The treatment groups after 14 d than those before the CSS score、TNF-α,IL-1 and IL-6 were decreased,the treatment group compared with the control group the decline was more obvious difference between the two groups was statistically significant (P0.05). Conclusion Danhong injection for the treatment of acute cerebral infarction can be a very good improvement in neurological function in patients may be related to the inhibition of cytokines TNF-α,IL-1 and IL-6 expression.