Laboratory study of the Natto Capsule on reducing blood Lipid in hyperlipemia model rats
FU Wei-zhong
Abstract
FU Wei-zhong
Abstract
Objective:To explore the effect of the Natto Capsule on reducing blood lipid in hyperlipemia model rats.Methods: The model of metabolic disturbance of lipid-preventive tested sample was adopted.After being given apocynum tea extract in dosages of 235 mg/kg,470 mg/kg,940 mg/kg BW respectively for 30 days,the contents of total cholesterol(TC),triglyceride(TG) and high-density lipoprotein cholesterol levels(HDL-C) in serum of rats were tested.Results: The contents of TC,TG and HDL-C in high dosage group were(2.315±0.491),(0.888±0.214)and(0.984±0.256)mmol/L respectively,were lower than the TC content(2.829±0.440) mmol/L and TG content(1.106±0.140) mmol/L and higher than HDL-C concentration of(0.750±0.172) mmol/L in high-fat control group,the differences were significant(P0.05).Conclusion: The concentrated tea of apocynum venetum leaf can reduce the contents of serum total cholesterol,serum triglyceride and increase high-density lipoprotein cholesterol levels.It suggests that the sample has a hypolipidemic effect.
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Objective:To explore the effect of the Natto Capsule on reducing blood lipid in hyperlipemia model rats.Methods: The model of metabolic disturbance of lipid-preventive tested sample was adopted.After being given apocynum tea extract in dosages of 235 mg/kg,470 mg/kg,940 mg/kg BW respectively for 30 days,the contents of total cholesterol(TC),triglyceride(TG) and high-density lipoprotein cholesterol levels(HDL-C) in serum of rats were tested.Results: The contents of TC,TG and HDL-C in high dosage group were(2.315±0.491),(0.888±0.214)and(0.984±0.256)mmol/L respectively,were lower than the TC content(2.829±0.440) mmol/L and TG content(1.106±0.140) mmol/L and higher than HDL-C concentration of(0.750±0.172) mmol/L in high-fat control group,the differences were significant(P0.05).Conclusion: The concentrated tea of apocynum venetum leaf can reduce the contents of serum total cholesterol,serum triglyceride and increase high-density lipoprotein cholesterol levels.It suggests that the sample has a hypolipidemic effect.
Key concepts: Triglyceride, Chemistry, Blood lipids, Dose, High-density lipoprotein, Total cholesterol, Cholesterol, Capsule