Effect analysis on low concentration of ropivacaine combined with sufentanil combined spinal epidural analgesia in childbirth

Objective To observe the effect of low concentration of ropivacaine combined with sufentanil combined spinal epidural anesthesia(CSEA) for labor analgesia, and discuss its feasibility, effects on mothers and adverse reaction.Methods Sixty pregnant women were randomly divided into the observation group and the control group with 30 cases in each group. In the observation group, when uterine neck opened about 3 cm, the L3-4 lumbar puncture was pertormed, and 5 μg sufentanil was injected into subarachnoid, the tube was placed cephalad into epidural cavity until 3.5 cm depth, epidural cavity was connected with a patient-controlled analgesia(PCA) pump. CSEA was performed using a mixture of 0.1% hydrochloric acid ropivacaine with 0.2 μg/ml of sufentanil administered in epidural cavity, in total 100 ml. The control group received routine treatment and did not use any analgesics. At 5, 10, 30, 60 and 90 min after analgesia VAS score, the duration of labor, mode of delivery, neonatal Apgar score, analgesic effect degree of satisfaction and adverse reaction were observed.Results VAS score between two groups had statistically significant difference. VAS score in observation group was lower than that in control group. Between two groups, the difference in the birth process, and postpartum hemorrhage were not statistically significance. Normal birth rate in the observation group was lower than that in control group(P0.01), the rate of using oxytocin in the observation group was higher than that in the control group(P0.05). The difference in mechanical delivery rate and cesarean section rate,neonatal Apgar score had not statistically significance between the two groups. Analgesia effect degree of satisfaction in observation group was better than that in the control group. Two cases with itch of skin were found in observation group,1 case with nausea and 1 cases with lower limb numbness in each group.Conclusion Low concentration of ropivacaine combined with sufentanil combined spinal epidural analgesia in childbirth had obvious effect and a long time of analygesia and its effect was quick. Although it will increase the rate of using oxytocin, but not affect the rate of cesarean section, with no harmful effects on mother and infant.