OBSERVATION OF ULINASTATIN COMBINED WITH SOMATOSTATIN IN TREATMENT OF SEVERE ACUTE PANCREATITIS

[Objective]To discuss the ulinastatin combined with somatostatin in treatment of severe acute pancreatitis.[Methods]62 patients diagnosed with severe acute pancreatitis were randomly divided into control group and treatment group,two groups were treated with conventional therapy,including fasting,gastrointestinal decompression,anti-inflammatory,inhibit pancreatic secretion symptomatic and supportive treatment.Treatment group based on the above was given ulinastatin,somatostatin,while somatostatin was used alone in the control group.14d was a course of treatment.Then compared the efficacy and clinical remission in the two groups.[Results]The extinction time of abdominal pain,the recovery time of urine amylase,the average hospitalization time in the treatment group were significantly shorter than in the control group(P﹤0.01).The total effective rate was statistically different(χ2 = 8.375,P﹤0.01).[Conclusion]Ulinastatin combined with somatostatin in treatment of severe acute pancreatitis has significant clinical effect,which can improve clinical symptoms and signs,it should be popularized and applied in clinic.