2014Chinese Journal of the Frontiers of Medical ScienceRequires access

Patients with acute severe pancreatitis somatostatin combined clinical analysis of ulinastatin treatment

OU Yun-son

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Abstract

Objective To observe the patients with severe acute pancreatitis with somatostatin combined the clinical curative effect of ulinastatin treatment, provide reference for clinical. Methods 81 patients with acute severe pancreatitis were randomly divided into two groups, two groups of both the conventional medicine combined somatostatin therapy, the observing group on the basis of this to the ulinastatin combined treatment, compared two groups of clinical curative effect. Results The total effective observation group 38 cases(92.68%), 30 cases(75.00%), control group total effective observation group total effective rate was higher than the control group(χ2= 4.698, P = 4.698). Abdominal pain, abdominal distension relief time observing group, the WBC recovery time, AMS recovery time, hospital stay is less than the control group(t = 3.040, 2.202, 2.067, 2.202, P 0.05 or 0.01); Experimental group 17.07% incidence of adverse reactions, the control group was 17.07%, no statistically significant differences between the two groups(χ2= 0.376, P = 0.376). Conclusion Patients with severe acute pancreatitis with somatostatin combined ulinastatin treatment the curative effect is superior to the use of somatostatin, and take effect quickly.

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Objective To observe the patients with severe acute pancreatitis with somatostatin combined the clinical curative effect of ulinastatin treatment, provide reference for clinical. Methods 81 patients with acute severe pancreatitis were randomly divided into two groups, two groups of both the conventional medicine combined somatostatin therapy, the observing group on the basis of this to the ulinastatin combined treatment, compared two groups of clinical curative effect. Results The total effective observation group 38 cases(92.68%), 30 cases(75.00%), control group total effective observation group total effective rate was higher than the control group(χ2= 4.698, P = 4.698). Abdominal pain, abdominal distension relief time observing group, the WBC recovery time, AMS recovery time, hospital stay is less than the control group(t = 3.040, 2.202, 2.067, 2.202, P 0.05 or 0.01); Experimental group 17.07% incidence of adverse reactions, the control group was 17.07%, no statistically significant differences between the two groups(χ2= 0.376, P = 0.376). Conclusion Patients with severe acute pancreatitis with somatostatin combined ulinastatin treatment the curative effect is superior to the use of somatostatin, and take effect quickly.

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Available abstract

Objective To observe the patients with severe acute pancreatitis with somatostatin combined the clinical curative effect of ulinastatin treatment, provide reference for clinical. Methods 81 patients with acute severe pancreatitis were randomly divided into two groups, two groups of both the conventional medicine combined somatostatin therapy, the observing group on the basis of this to the ulinastatin combined treatment, compared two groups of clinical curative effect. Results The total effective observation group 38 cases(92.68%), 30 cases(75.00%), control group total effective observation group total effective rate was higher than the control group(χ2= 4.698, P = 4.698). Abdominal pain, abdominal distension relief time observing group, the WBC recovery time, AMS recovery time, hospital stay is less than the control group(t = 3.040, 2.202, 2.067, 2.202, P 0.05 or 0.01); Experimental group 17.07% incidence of adverse reactions, the control group was 17.07%, no statistically significant differences between the two groups(χ2= 0.376, P = 0.376). Conclusion Patients with severe acute pancreatitis with somatostatin combined ulinastatin treatment the curative effect is superior to the use of somatostatin, and take effect quickly.

Key concepts: Ulinastatin, Medicine, Abdominal distension, Somatostatin, Acute pancreatitis, Pancreatitis, Gastroenterology, Abdominal pain

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