2012Chinese Journal of Experimental and Clinical Infectious DiseasesRequires access

Clinical study on meropenem in the treatment of bacterial infection

Jiang Xiu-fan

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Abstract

Objective To evaluate the efficacy and safety of domestic meropenem (Beineng) injection in treatment of severe bactenal infection. Methods A randomized controlled clinical trial was conducted,while the imported meropenem (Mepem) was used as the control. Results The overall efficacy rates of Beineng and Mepem were 81.60% and 82.39%,respectively. The bacterial clearance rates were 88.64% and 91.10%,respectively. The incidence rates of adverse reaction were 5.52% and 5.11%,respectively. There was no significant difference between the two groups for the above results. Conclusions Domestic meropenem (Beineng) injection is an antibacterial agent for bacterial infection with high efficacy and safety.

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What this paper is about

Objective To evaluate the efficacy and safety of domestic meropenem (Beineng) injection in treatment of severe bactenal infection. Methods A randomized controlled clinical trial was conducted,while the imported meropenem (Mepem) was used as the control. Results The overall efficacy rates of Beineng and Mepem were 81.60% and 82.39%,respectively. The bacterial clearance rates were 88.64% and 91.10%,respectively. The incidence rates of adverse reaction were 5.52% and 5.11%,respectively. There was no significant difference between the two groups for the above results. Conclusions Domestic meropenem (Beineng) injection is an antibacterial agent for bacterial infection with high efficacy and safety.

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Available abstract

Objective To evaluate the efficacy and safety of domestic meropenem (Beineng) injection in treatment of severe bactenal infection. Methods A randomized controlled clinical trial was conducted,while the imported meropenem (Mepem) was used as the control. Results The overall efficacy rates of Beineng and Mepem were 81.60% and 82.39%,respectively. The bacterial clearance rates were 88.64% and 91.10%,respectively. The incidence rates of adverse reaction were 5.52% and 5.11%,respectively. There was no significant difference between the two groups for the above results. Conclusions Domestic meropenem (Beineng) injection is an antibacterial agent for bacterial infection with high efficacy and safety.

Key concepts: Meropenem, Medicine, Incidence (geometry), Adverse effect, Clinical efficacy, Clinical trial, Significant difference, Randomized controlled trial

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