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Analysis of 121 Adverse Drug Reaction Reports

Jiang Han-ying

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Abstract

Objective To investigate the characteristics of adverse drug reactions(ADRs) in Tongji hospital,and know well ADR monitoring and assessment for avoiding risk of drug use in clinic.Methods ADR reports in our hospital from September 1,2008 to August 31,2010 were downloaded from the national and municipal ADR monitoring network.The related data were converted and analyzed statistically.Results Among the 121 ADR cases of medication,antimicrobial agents ranked firstly and followed by the antitumor agents and drugs on circulation system.The main ADRs involved systemic disorders,skin and its appendage damages,and digestive system disorders.Ninety ADR cases(74.4%) were induced by intravenous drip.There were 19 new and serious ADR reports,which related to 16 kinds of medicines.Conclusion It should be paid more attention to establishing high-level ADR monitoring system,carrying out the analysis,tracking high risk medicines,expanding safe research and promulgating precaution to deminish the drug risk.

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Objective To investigate the characteristics of adverse drug reactions(ADRs) in Tongji hospital,and know well ADR monitoring and assessment for avoiding risk of drug use in clinic.Methods ADR reports in our hospital from September 1,2008 to August 31,2010 were downloaded from the national and municipal ADR monitoring network.The related data were converted and analyzed statistically.Results Among the 121 ADR cases of medication,antimicrobial agents ranked firstly and followed by the antitumor agents and drugs on circulation system.The main ADRs involved systemic disorders,skin and its appendage damages,and digestive system disorders.Ninety ADR cases(74.4%) were induced by intravenous drip.There were 19 new and serious ADR reports,which related to 16 kinds of medicines.Conclusion It should be paid more attention to establishing high-level ADR monitoring system,carrying out the analysis,tracking high risk medicines,expanding safe research and promulgating precaution to deminish the drug risk.

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Available abstract

Objective To investigate the characteristics of adverse drug reactions(ADRs) in Tongji hospital,and know well ADR monitoring and assessment for avoiding risk of drug use in clinic.Methods ADR reports in our hospital from September 1,2008 to August 31,2010 were downloaded from the national and municipal ADR monitoring network.The related data were converted and analyzed statistically.Results Among the 121 ADR cases of medication,antimicrobial agents ranked firstly and followed by the antitumor agents and drugs on circulation system.The main ADRs involved systemic disorders,skin and its appendage damages,and digestive system disorders.Ninety ADR cases(74.4%) were induced by intravenous drip.There were 19 new and serious ADR reports,which related to 16 kinds of medicines.Conclusion It should be paid more attention to establishing high-level ADR monitoring system,carrying out the analysis,tracking high risk medicines,expanding safe research and promulgating precaution to deminish the drug risk.

Key concepts: Medicine, Adverse drug reaction, Drug reaction, Drug, Damages, Emergency medicine, Intensive care medicine, Pharmacology

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