Analysis of 540 Cases of Adverse Drug Reaction in Our Hospital

OBJECTIVE: To investigate hospital adverse drug reactions ( ADR) occurrence,promote clinical rational drug use,improve the level of ADR monitoring. METHODS: Analyze 540 cases of ADR reports in our hospital collected from June 2004 to June 2009 by retrospective analysis,including the patients′ age and gender,route of administration,drug type,ADR involving the organ /system,the first eight drugs triggering ADR,the quality of ADR reporting. RESULTS: The incidence rate of ADR is more in women than in men; Anti infective drugs and proprietary Chinese medicine ranked 1,2;intravenous infusion of drug induced accounted for 82. 04% ;ADR involved the organ / system mainly in skin and its annexes,accounted for 48. 52% . The highest incidence of ADR drugs is cefotaxime sodium for injection. CONCLUSION: It should be to have a correct understanding to the importance of ADR monitoring,strengthen monitoring and advocacy in ADR,effort to improve the quality of ADR reports to ensure patient safety in drug use.