A Pharmacology Study of Tang-zhi-ping Treatment on Mice' Experimental Diabetes

Objective To investigate the effect of a herba product--Tang\|zhi\|ping on blood sugar in normal and experimental diabetic mice. Methods The mice were treated with Tang\|zhi\|ping at doses of 3 5, 7 0 and 14 0 g/kg one time a day for 5 days. Experimental diabetic models were induced by adrenalin, glucose or alloxan. Results Tang\|zhi\|ping kept the stability of fasting blood sugar in normal mice, and significantly decreased blood sugar of diabetic mice. The largest enduring dose of Tang\|zhi\|ping for mice was 68 75 g/kg ig daily, which is 395 times as the dose for adult patient. Conclusion Tang\|zhi\|ping has hypoglycemic effect and very little toxicity.\;