2009•Traditional Chinese MedicineRequires access
Experimental Study on Tang-zhi-ping Granule Leading to Actue Toxicity of Mice
Cui-zhen Dong
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Abstract
Objective To study the acute toxic reaction of Tang-zhi-ping granule on mice. Methods The maximum concentration of Tang-zhi-ping granule was administrated to mice with no dead mice was found. LD50 did not be found, so we detected the maximum administration dosage. Results The maximum administration dosage of tang-zhi-ping granule was 85.72 g/kg, equaling to 296 times of clinical daily dose which is 0.29 g/kg. Conclusion Tang-zhi-ping granule is determined by acute toxicity study to be safe and having no toxicity.
Key words:
Tang-zhi-ping granule; Actue toxicity; mice