The investigation of jiang tang ming mu tang's effect on the blood glucose and weight in diabetic mice model

Objective To observe the effect of jiang tang ming mu tang on the blood glucose and weight in streptozocin induced diabetic mice model in order to investigate the mechanism of jiang tang ming mu tang for the treatment of diabetic retinopathy.Methods Forty C57BL/B mice were randomly divided into 4 groups. Group A:normal control group; group B:normal mice fed jiang tang ming mu tang ; group C: diabetic mellitus group; group D: diabetic mellitus mice fed jiang tang ming mu tang . The diabetic C57BL/B mice model was induced by streptozocin. Empty stomach blood glucose and weight were recorded at 1day, 7days, 30days, 60days and 80days after the diabetic models were induced.Results The diabetic models were induced by STZ. Compared to the group C ,the level of empty stomach blood glucose was lower and weight was heavier in group D ,but there were no significant differences(P0.05).Conclusion Jiang tang ming mu tang was demonstrated having effect of treating early diabetic retinopathy in clinic. Our experiment show that jiang tang ming mu tang has no significant influence on blood glucose and weight in diabetic mice model , and manifest that jiang tang ming mu tang dose not have effect on diabetic retinopathy through reducing blood glucose. So jiang tang ming mu tang's mechanism for inhibiting diabetic retinopathy still needs further investigation.